This GLP-1 titration schedule calculator turns the standard dose escalation into a week-by-week table in mg, mL, and insulin syringe units for your vial.
How to use the GLP-1 Titration Schedule Calculator
- Choose the medication.
- Enter the vial size, or tap a preset.
- Enter the bac water added, or tap a preset.
- Choose the syringe type.
- Read the result card. It updates as you type, and you can copy or share it.
About this calculator
GLP-1 medications start low and step up every 4 weeks to reduce stomach side effects. The semaglutide and tirzepatide schedules follow the FDA-approved Wegovy and Zepbound labels. Retatrutide is investigational and its schedule reflects a published phase 2 trial arm.
Your prescriber may hold a dose longer, step down, or stop escalating at a lower maintenance dose.
Frequently asked questions
What if I miss a week?
Label guidance differs by medication and how long ago the dose was due. Follow your prescriber’s instructions or the medication guide.
Why does the unit count grow so much?
The concentration stays fixed while the dose increases, so volume rises in proportion. A more concentrated vial keeps high doses within a smaller syringe.
Sources
- Wegovy (semaglutide) injection: prescribing information. DailyMed, National Library of Medicine.
- Zepbound (tirzepatide) injection: prescribing information. DailyMed, National Library of Medicine.
- Jastreboff AM et al. Triple-hormone-receptor agonist retatrutide for obesity. N Engl J Med. 2023;389:514–526. New England Journal of Medicine.
Related calculators
- Semaglutide Calculator: This Semaglutide calculator shows how many units to draw after reconstituting a Semaglutide vial. It includes common vial sizes, half-life, and storage notes.
- Tirzepatide Calculator: This Tirzepatide calculator shows how many units to draw after reconstituting a Tirzepatide vial. It includes common vial sizes, half-life, and storage notes.
- Retatrutide Calculator: This Retatrutide calculator shows how many units to draw after reconstituting a Retatrutide vial. It includes common vial sizes, half-life, and storage notes.
- Peptide Half-Life Calculator: This peptide half-life calculator charts estimated levels over time so you can see how doses accumulate and when steady state is reached.
Medical disclaimer. This calculator is for educational purposes only and is not medical advice. Results are mathematical estimates based on the values you enter. Many peptides listed here are not approved by the FDA for human use. Confirm every dose with a licensed healthcare provider or your approved study protocol, and follow the product label.


